While I don't know if my own experience with technology agrees with everything Sherry Turkle says in this talk, many of the points she raises I find really relevant to my masters research. Particularly her points on how we define ourselves by what we share and how we edit/present the self with new media - I would argue though that this can still be just as clumsy and awkward in any social situation, on or offline. Reading peoples posts on Facebook or Twitter appears to be full of unintended stumbling and revealing moments.
New technology does change us... but I don't think we should see it as a passive cause and effect exchange and I guess this is the point Turkle does make at the end about self-reflection.
I'm interested to hear from others on this subject.